A study by the German Institute of Human Nutrition showed that foods containing mixed artificial sweeteners, such as sugar-free sodas, "close" bitter receptors and affect subsequent eating.
The researchers analyzed taste receptor responses to two common sweeteners, saccharin and cyclamate, and their mixture. Saccharin and cyclamate were the earliest blends of two sweeteners. It was discovered more than 60 years ago that the mixture was better than "single use," but the reason remains unclear.
The researchers identified bitter and sweet receptors that activate and inhibit saccharin and cyclamate, respectively. The results show that a bitter receptor that is inhibited by saccharin is activated by cyclamate, and two bitter receptors inhibited by cyclamate are activated by saccharin. When a mixture of saccharin and cyclamate was ingested, some of the subjects' 25 bitter taste receptors were immediately "closed."
The British "Daily Mail" on the 14th quoted the research group leader Mike Behrens as saying that the suppression of bitter receptors will affect the consumption of other bitter foods, such as alcoholic beverages, which makes it easy to overdose. However, this can also be a good thing. It can be used to improve the taste of medicines so that oral medicines no longer suffer.
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