The British "Nature-Nanotechnology" magazine published an "injectable circuit" study online on the 8th. The paper demonstrates a flexible circuit that can be injected into a synthetic cavity or living tissue through a needle having a diameter as small as 0.1 mm. These electronic components composed of mesh electrodes can be unfolded to their original shape and function without function within one hour after injection. Experiments have shown that it can be used to monitor brain activity in mice.
Flexible and extensible electronic components can be used to continuously monitor and manipulate some three-dimensional structural properties, such as biological tissue. Studies in the past have shown that bio-integrated microelectronics needs and can adapt to the intricate structure of the brain, but in practice, these electronic components can only be implanted by surgery, put them in specific areas, and still can't do it. To non-invasive implants.
Today, internationally renowned top nano scientists, Charles Libo of Harvard University, and Fang Ying of China National Nanoscience Center, led their research team to design a mesh circuit that can be placed in a syringe and then passed through a small diameter. A needle of 0.1 mm is injected into a specific area of ​​the synthetic cavity or living tissue.
The authors said that after being injected, the original "rolled up" circuit would expand to nearly 80% of the original configuration and would not lose functionality. The researchers injected the circuit into two different regions of the brain of a living mouse. During the five-week period, they did not produce a rejection reaction, and the circuit showed connections to healthy neurons. When microcircuits were injected into the hippocampus of mice, the researchers found that microcircuits can monitor brain activity and have limited damage to surrounding brain tissue.
The functions of artificially implanted electronic components in the body, the compatibility with the organism's own organs, and the size manufacturing process are all being upgraded, and the subsequent implantation methods are becoming more and more sophisticated. In the journalism and opinion articles related to this paper in Nature, the review authors Jin Dazhao and Li Yongzhi wrote: "In the future, combined with injectable circuits with other functional units (which can also have wireless units), will guide Innovations in implanting biocircuits and ongoing biomonitoring technologies."
More than a decade ago, people tried to put tiny circuits into the brains of mice. Even though the most advanced electronic components were used in this technology at the time, these circuits were still "sanded" into a small "sand". The brain of the rat, a series of rejections, made it painful. Today, the flexible circuit and its syringe jointly developed by China and the United States have brought hope for solving problems that have plagued brain scientists for many years. If these tiny circuits are too hard and have limited brain damage, we have every reason to believe that it will help humans open a new door to brain science.
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